Once believed to be acting independently, we now know that the top three most wanted criminals have in fact been working together for some time. Why these homicidal maniacs chose to join forces remains a mystery, but all agree that the union of Buzz Kill, Manhkee, and S-O-G means death, destruction, and mayhem for our city and its inhabitants. According to recent intelligence, this alliance of pure evil called The Murderers is in league with a mad scientist of sorts. It is alleged that this scientist has physically altered each member of the organization to better suit their individual personalities and killing styles, and may very well prove to be the mastermind of the operation.
The efforts of law enforcement agencies and private security firms have thus far been ineffective against The Murderers. The only party to achieve favorable results against this gang of mutants is Test Subject 000. Although not working in cooperation with the authorities and often breaking the law himself, Test Subject 000, or Triple Zero as some call him, has a very personal interest in bringing the mad scientist to justice.